Validation report

ID OBO Namespace Label Exact Synonym Exact Synonym with Reference Synonym Reference Broad Synonym Synonym Reference Related Synonym Synonym Reference Database Cross Reference Definition Definition Source Comment OBO Creator OBO Creation Date DC Creator DC Creation Date Class Type Parent Only In Taxon Asserted Parent Disjoint With Capable Of Has Plasma Membrane Part Lacks Plasma Membrane Part High Amount Low Amount Develops From Other Axioms
is-required true; subclass-of 'cell'
XCL:H1 human cell equivalent cell Homo sapiens
XCL:H2 human lymphocyte equivalent lymphocyte Homo sapiens
CL:0000938 cell CD16-negative, CD56-bright natural killer cell CD16-negative, CD56-bright NK cell|CD56-bright cytokine secreting natural killer cell|CD56-bright cytokine secreting NK cell CD16-CD56bright NK cell PMID:22343568 NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. GOC:add|GOC:pam|GOC:tfm|GO_REF:0000031|PMID:19796267|PMID:22343568 This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types. equivalent mature natural killer cell Homo sapiens interferon-gamma production SLAM family member 5 low affinity immunoglobulin gamma Fc region receptor III|MHC class II histocompatibility antigen alpha chain DRA neural cell adhesion molecule 1
CL:0000939 cell CD16-positive, CD56-dim natural killer cell CD16-positive, CD56-dim NK cell|CD16-positive, CD56-low natural killer cell|CD16-positive, CD56-low NK cell|CD16-positive, CD56-positive natural killer cell|CD16-positive, CD56-positive NK cell|cytotoxic CD56-dim natural killer cell|cytotoxic CD56-dim NK cell CD16+CD56+ NK cell PMID:22343568 A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production. GOC:add|GOC:pam|GO_REF:0000031|PMID:19796267|PMID:22343568 This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types. equivalent mature natural killer cell Homo sapiens cytokine production|natural killer cell mediated cytotoxicity low affinity immunoglobulin gamma Fc region receptor III MHC class II histocompatibility antigen alpha chain DRA neural cell adhesion molecule 1
CL:0002344 cell CD56-negative, CD161-positive immature natural killer cell p-NK PMID:12457618 A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. GOC:add|GO_REF:0000031|ISBN:0781735149|PMID:12457618 Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). tmeehan 2010-09-20T04:33:11Z equivalent immature natural killer cell Homo sapiens interleukin-2 receptor subunit beta|KLRB1-like protein|mast/stem cell growth factor receptor CD34 molecule|neural cell adhesion molecule 1
CL:0002338 cell CD56-positive, CD161-positive immature natural killer cell p-NK PMID:12457618 A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. GOC:add|GO_REF:0000031|ISBN:0781735149|PMID:12457618 Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily). tmeehan 2010-09-21T10:06:53Z equivalent immature natural killer cell Homo sapiens neural cell adhesion molecule 1|interleukin-2 receptor subunit beta|KLRB1-like protein|mast/stem cell growth factor receptor CD34 molecule CD56-negative, CD161-positive immature natural killer cell
CL:0002343 cell decidual natural killer cell decidual NK cell|dNK cell A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy. PMID:14568979|PMID:19800965 tmeehan 2010-09-20T04:00:02Z equivalent mature natural killer cell Homo sapiens galectin-1 low affinity immunoglobulin gamma Fc region receptor III neural cell adhesion molecule 1
Homo sapiens
CL:0001072 CD34-negative, CD117-positive innate lymphoid cell CD34-negative, CD117-positive ILC|CD34-negative, CD117-positive ILCP|CD34-negative, CD117-positive innate lymphoid cell precusor An innate lymphoid cell in the human with the phenotype CD34-negative, CD117-positive, and a precusor to NK cells, ILC2 cells, and ILC3 cells. GOC:add|PMID:31201208|PMID:30193847 equivalent innate lymphoid cell Homo sapiens mast/stem cell growth factor receptor Kit (human) hematopoietic progenitor cell antigen CD34 (human) CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor ('bearer of' some immature)
CL:0001073 CD34-negative, CD56-positive, CD117-positive innate lymphoid cell CD34-negative, CD56-positive, CD117-positive ILC|CD34-negative, CD56-positive, CD117-positive ILCP|CD34-negative, CD56-positive, CD117-positive innate lymphoid cell precursor An innate lymphoid cell in the human with the phenotype CD34-negative, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. GOC:add|PMID:31201208|PMID:30193847 equivalent CD34-negative, CD117-positive innate lymphoid cell Homo sapiens neural cell adhesion molecule 1 (human)|mast/stem cell growth factor receptor Kit (human)
CL:0001074 CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor CD34-positive, CD56-positive, CD117-positive CILP An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. GOC:add|PMID:30193847 equivalent innate lymphoid cell Homo sapiens hematopoietic progenitor cell antigen CD34 (human)|neural cell adhesion molecule 1 (human)|mast/stem cell growth factor receptor Kit (human) ('bearer of' some immature)
CL:0001075 KLRG1-positive innate lymphoid cell KLRG1-positive ILC An innate lymphoid cell in the human with the phenotype KLRG1-positive that is a precusor for ILC2 cells. GOC:add|PMID:31201208 equivalent CD34-negative, CD117-positive innate lymphoid cell Homo sapiens killer cell lectin-like receptor subfamily G member 1 (human)
CL:0001076 NKp46-positive innate lymphoid cell NKp46-positive ILC An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells. GOC:add|PMID:31201208|PMID:31337734 equivalent CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor Homo sapiens natural cytotoxicity triggering receptor 1 (human)
CL:0001077 ILC1, human innate lymphoid cell 1, human An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive. GOC:add|PMID:31500958 equivalent ILC1 Homo sapiens interleukin-7 receptor subunit alpha (human) ('has part' some 'T-box transcription factor TBX21 (human)')
CL:0001078 group 3 innate lymphoid cell, human ILC3, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive and CD69-positive. GOC:add|PMID:31500958 equivalent group 3 innate lymphoid cell Homo sapiens interleukin-7 receptor subunit alpha (human)|early activation antigen CD69 (human)
CL:0001079 NKp44-positive group 3 innate lymphoid cell, human ILC3, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, CD69-positive, and NKp44-positive. GOC:add|PMID:31500958|PMID:24778151 equivalent group 3 innate lymphoid cell Homo sapiens interleukin-7 receptor subunit alpha (human)|early activation antigen CD69 (human)|natural cytotoxicity triggering receptor 2 (human)
CL:0001080 NKp44-negative group 3 innate lymphoid cell, human ILC3, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, CD69-positive, and NKp44-negative. GOC:add|PMID:31500958|PMID:24778151 equivalent group 3 innate lymphoid cell Homo sapiens interleukin-7 receptor subunit alpha (human)|early activation antigen CD69 (human) natural cytotoxicity triggering receptor 2 (human)
CL:0001081 group 2 innate lymphoid cell, human ILC2, human A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive. GOC:add|PMID:24778151|PMID:26844414 equivalent group 2 innate lymphoid cell Homo sapiens interleukin-2 receptor subunit alpha (human)|interleukin-7 receptor subunit alpha (human)|killer cell lectin-like receptor subfamily B member 1 (human) ('has part' some 'trans-acting T-cell-specific transcription factor GATA-3 (human)')