A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR).
In mouse the NKR are Ly49 molecules and in human these cells express KIR molecules.
A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules.
Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins.
These cells are also reportedly CD7-low, CD10-negative, CD45RA-positive, alpha-4-beta-7 integrin-high.
NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic.
CD56-bright cytokine secreting natural killer cell
This cell type is compatible with the HIPC Lyoplate markers for 'CD16-CD56bright NK cell'. Markers are associated with human cell types.
CD16-negative, CD56-bright natural killer cell
A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production.
CD16-positive, CD56-low natural killer cell
CD16-positive, CD56-positive natural killer cell
This cell type is compatible with the HIPC Lyoplate markers for 'CD16+CD56+ NK cell'. Markers are associated with human cell types.
CD16-positive, CD56-dim natural killer cell
A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses.
An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines.
A group 1 innate lymphoid cell that is non-cytotoxic.
An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation.
An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22.
An innate lymphoid cell in the human with the phenotype CD34-negative, CD117-positive, and a precusor to NK cells, ILC2 cells, and ILC3 cells.
CD34-negative, CD117-positive innate lymphoid cell precusor
CD34-negative, CD117-positive innate lymphoid cell
An innate lymphoid cell in the human with the phenotype CD34-negative, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells.
CD34-negative, CD56-positive, CD117-positive ILC
CD34-negative, CD56-positive, CD117-positive ILCP
CD34-negative, CD56-positive, CD117-positive innate lymphoid cell precursor
CD34-negative, CD56-positive, CD117-positive innate lymphoid cell
An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells.
CD34-positive, CD56-positive, CD117-positive CILP
CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor
An innate lymphoid cell in the human with the phenotype KLRG1-positive that is a precusor for ILC2 cells.
An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells.
An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive.
A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive and CD69-positive.
A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, CD69-positive, and NKp44-positive.
NKp44-positive group 3 innate lymphoid cell, human
A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, CD69-positive, and NKp44-negative.
NKp44-negative group 3 innate lymphoid cell, human
A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive.
An innate lyphoid cell with an immature phenotype.
A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive.
Human markers; killer cell immunoglobulin-like receptor 2DL1 is used as a representative example (PRO at this time lacks a KIR superfamily).
CD56-positive, CD161-positive immature natural killer cell
A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy.
CD56-negative, CD161-positive immature natural killer cell
A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid.
Pit cells are named for the presence of large cytoplasmic granules that resemble pits (pips) of fruit.
positive regulation of type 2 immune response
natural killer cell mediated cytotoxicity
T-cell surface glycoprotein CD8 alpha chain
membrane-spanning 4-domains subfamily A member 1
killer cell lectin-like receptor subfamily D member 1
low affinity immunoglobulin gamma Fc region receptor III
natural cytotoxicity triggering receptor 1
MHC class II histocompatibility antigen alpha chain DRA
NKG2-A/NKG2-B type II integral membrane protein
killer cell lectin-like receptor subfamily B member 1C
high affinity immunoglobulin epsilon receptor subunit alpha
natural cytotoxicity triggering receptor 1 (human)
natural cytotoxicity triggering receptor 2 (human)
interleukin-2 receptor subunit alpha (human)
mast/stem cell growth factor receptor Kit (human)
interleukin-7 receptor subunit alpha (human)
trans-acting T-cell-specific transcription factor GATA-3 (human)
hematopoietic progenitor cell antigen CD34 (human)
killer cell lectin-like receptor subfamily B member 1 (human)
killer cell lectin-like receptor subfamily G member 1 (human)
T-box transcription factor TBX21 (human)